Paula's Choice CellularYouth Longevity Serum
Skincare authority Paula’s Choice has entered the longevity category with its CellularYouth Longevity Serum. Developed over five years, the new serum is the most extensively researched formulation in the brand's history. It arrives as the "longevity economy" gains traction in prestige beauty, with brands pivoting to meet the needs of an active baby boomer demographic.
The CellularYouth Longevity Serum addresses 12 visible signs of aging, such as sagging, fine lines, and uneven tone, by focusing on cellular fatigue. The formulation uses NAD+ supporting technology to maintain the skin’s natural energy cycle. As cellular energy declines, natural renewal slows and effectively speeds up the aging process, that’s where this formula comes in to recharge those natural repair pathways.
Key ingredients include:
Age-Disrupting Complex: A combination of Longevity Peptides and Taurine to extend a youthful appearance.
Sunflower Sprout Extract: A nutrient-rich extract that fuels the NAMPT enzyme, which is essential for regenerating NAD+.
Goji Phyto-Exosomes: Used to tighten contours and improve skin firmness.
Acetyl Tetrapeptide-2: A peptide designed to promote skin renewal for a smoother texture.
In a supplier clinical study, the serum helped skin appear up to eight years younger after 42 days of use. Consumer perception trials supported these results, with 100% of participants reporting more youthful and firmer skin within three weeks.
The product's strategy reflects an industry shift toward "pro-aging" messaging. By focusing on "skin healthspan" instead of "anti-aging," Paula’s Choice is aligning with wellness trends that value long-term vitality.
Available exclusively at Sephora from 22 January 2026.
