ESK Ultimate A Gold

ESK Evidence Skincare has launched Ultimate A Gold, a next generation retinoid night cream co-created with actor and advocate Selma Blair. The brief is simple: clinical results with real comfort, especially for people who find traditional vitamin A too irritating. Blair’s own history of reactive, autoimmune-affected skin shaped the project, which she developed hands-on with ESK founder and physician Dr Ginni Mansberg.

At its core is 0.1 percent retinal, a potent vitamin A that speeds skin renewal without the typical sting, supported by a cast of barrier-first allies. The formula layers 5 percent niacinamide to calm and strengthen, 5 percent lactobionic acid for water-binding, gentle resurfacing, and 0.06 percent ceramides to shore up the lipid matrix. Hydration comes from 1.5 percent hyaluronic acid, while 2 percent ectoin helps skin hold water and stay resilient through daily stress. For tone, 0.1 percent 4-n-butylresorcinol targets stubborn pigmentation. The synergy is the point, each active is dosed to work, while cushioning the retinal so sensitive complexions can tolerate nightly use.

The positioning feels personal as well as clinical. Blair describes the cream as “personal, powerful, and rooted in real science,” while Dr Mansberg frames the collaboration as an evidence-led answer for delicate skin that still wants visible change.

“From the very first conversation with Selma, it was clear this wasn’t going to be a typical celebrity collaboration. Selma brought not only her personal story of struggling with sensitive, reactive skin, but also a genuine passion for science and integrity in skincare,” said Dr. Ginni Mansberg. “Together, we created Ultimate A Gold - a night cream that delivers clinical-level results while remaining gentle enough for the most delicate skin. This launch represents everything ESK stands for: evidence, transparency, and results without compromise.”

Known for its evidence-based formulas and straight-talk approach, ESK has built a following among dermatology-curious consumers who want clear actives, clear percentages and sensible routines. Partnering with Blair underscores that ethos and widens the conversation to those who have felt overlooked by high-octane skincare.

Ultimate A Gold is available now at eskcare.com.